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KMID : 0359819930220111175
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Journal of Korean Neurosurgical Society
1993 Volume.22 No. 11 p.1175 ~ p.1183
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Postoperative Intratumoral Injection of Bleomycin for Cystic Craniopharyngioma
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Abstract
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Surgical excision or irradiation of craniopharyngioma is problematic because both are often associated with high risk of complications. Three cases of cystic craniopharyngioma were subtotally removed by surgery and followed by repeated injection
of
bleomycin into the remaining tujor cavity as postoperative adjuvant therapy. With bleomycin injection. tujors were shrunk postoperatively in two cases out of three but in one case cyctic portion became increased in size progressively which needed
second
operation and irradiation. Bleomycin injection could be considered as one of the reasonable alternative adjuvant therapies for incompletely removed cystic craniopharyngioma before radiation therapy.
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KEYWORD
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